Publications - Horizon 21

Our publications

2025

Validation of the CAMCOG-DS-II, a neuropsychological test battery for Alzheimer’s disease in people with Down syndrome: A Horizon 21 European Down syndrome Consortium study

Phoebe Ivain, Asaad Baksh, Fedal Saini, Mina Idris, Miren Tamayo-Elizalde, Jasmine Wells, Bessy Benejam, Sandra Virginia Loosli, Katja Sandkühler, Elisabeth Wlasich, Olivia Wagemann, Johannes Levin, Diane Martet, Silvia Sacco, Ségolène Falquero, Manon Clert, Anne-Sophie Rebillat, Wan Ming Khoo, Madelaine Amelia Smith, Jessica Beresford-Webb, Shahid Zaman, María Carmona-Iragui, Laura Videla, Juan Fortea, Ellen Melbye Langballe, Ingrid Tøndel Medbøen, Frode Kibsgaard Larsen, Eleni Baldimtsi, Raphaella Paradisi, Panagiotis Ntailakis, Magdalini Tsolaki, Georgia Papantoniou, Eimear McGlinchey, Mary McCarron, Seán Kennelly, André Strydom

Alzheimer’s & Dementia March 2025

2024

Age of Alzheimer’s disease diagnosis in peoplewith Down syndrome and associated factors: Results from the Horizon 21 European Down syndrome consortium

Frode Kibsgaard Larsen, R. Asaad Baksh, Eimear McGlinchey, EllenMelbye Langballe, Bessy Benejam, Jessica Beresford-Webb, Mary McCarron, Antonia Coppus, Segolene Falquero, Juan Fortea, Johannes Levin, Sandra V. Loosli, Ruth Mark, Anne-Sophie Rebillat, Shahid Zaman, Andre Strydom

Alzheimer’s & Dementia February 2024

2024

Measurement properties of the German version of the Cambridge examination for mental disorders of older people with Down syndrome and others with intellectual disabilities (CAMDEX-DS)

Sandra V. Loosli, Lennart C. Neumann, Elisabeth Wlasich, Catharina Prix, Laura Koll, Endy Weidinger, Jonathan Vöglein, Olivia Wagemann, Adrian Danek, Georg Nübling & Johannes Levin

Journal of Intellectual & Developmental Disability, February 2024

2023

Common mental health disorders and cognitive decline in a longitudinal Down syndrome cohort

Idris M, Saini F, Pape SE, Baksh RA, Cahart MS, Strydom A

Cambridge University Press November 2023

2023

Exploring semantic verbal fluency patterns and their relationship to age and Alzheimer’s disease in adults with Down syndrome

Mgaieth F, Baksh RA, Startin CM, Hamburg S, Hithersay R, Pape S, Zetterberg H, Ashton NJ, Tamayo-Elizalde M, Saini F, Idris M, Consortium TL, Strydom A

The Journal of the Alzheimer’s Association April 2023

2021

The Clinical and Neuropathological Features of Sporadic (Late-Onset) and Genetic Forms of Alzheimer’s Disease

T. Rujeedawa, E. Carrillo Félez, I. C. H. Clare, J. Fortea, A. Strydom, AS. Rebillat, A. Coppus, J. Levin, S. H. Zaman

Journal of Clinical Medicine, October 2021

2021

Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study

M. Carmona-Iragui, D. Alcolea, I. Barroeta, L. Videla, L. Muñoz, K. L Van Pelt, F. A Schmitt, D. D Lightner, L. M Koehl, G. Jicha, S. Sacco, C. Mircher, S. E Pape, R. Hithersay, I. C H Clare, A. J Holland, G. Nübling, J. Levin, S. H Zaman, A. Strydom, A-S Rebillat, E. Head, R. Blesa, A. Lleó, J. Fortea

The Lancet, Neurology, August 2021

2021

Low-degree trisomy 21 mosaicism promotes early-onset Alzheimer disease

Nübling, G. S., Prix, C., Brendel, M., Beyer, L., Wlasich, E., Loosli, S. V., Barthel, H., Sabri, O., Bartenstein, P., Vöglein, J., Danek, A., Rominger, A., Edbauer, D., Haass, C., Levin, J.

Neurobiology of Aging, July 2021

2021

Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer’s disease

J. Aschenbrenner, R. A. Baksh, B. Benejam, J. A. Beresford-Webb, A. Coppus, J. Fortea, B. L. Handen, S. Hartley, E. Head, J. Jaeger, J. Levin, S. V. Loosli, A.-S. Rebillat, S. Sacco, F. A. Schmitt, K. E. Thurlow, S. Zaman, J. Hassenstab, A. Strydom

Alzheimer’s Dementia, 19 April 2021

2021

Prognostic performance and longitudinal changes in plasma Neurofilament light levels in adults with Down syndrome: a multicentre longitudinal study

M. Carmona-Iragui, D. Alcolea, I. Barroeta, L. Videla, L. Muñoz, K. Van Pelt, F. Schmitt, D. Lightner, L. Koehl, G. Jicha, S. Sacco, C. Mircher, S. Pape, R. Hithersay, I. Clare, A. Holland, G. Nübling, J. Levin, S. Zaman, A. Strydom A.-S. Rebillat, E. Head, R. Blesa, A. Lleó, J. Fortea

The Lancet Neurology, 16 Apr 2021

2021

Opportunities, barriers, and recommendations in Down syndrome research

Hendrix James A, Amon Angelika, Abbeduto Leonard, Agiovlasitis Stamatis, Alsaied Tareke, Anderson Heather A., Bain Lisa J., Baumer Nicole, Bhattacharyya Anitai, Bogunovic Dusan, Botteron Kelly N., Capone George, Chandan Priya, Chase Isabelle, Chicoine Brian, Cieuta-Walti Cécile, DeRuisseau Lara R., Durand Sophie, Esbensen Anna, Fortea Juan, Giménez Sandra, Granholm Ann-Charlotte, Mattie Laura J., Head Elizabeth, Hillerstrom Hampus, Jacola Lisa M., Janicki Matthew P., Jasien Joan M., Kamer Angela R., Kent Raymond D., Khor Bernard, Lawrence Jeanne B., Lemonnier Catherine, Lewanda Amy Feldman, Mobley William, Moore Paul E., Nelson Linda Pollak, Oreskovic Nicolas M., Osorio Ricardo S., Patterson David, Rasmussen Sonja A., Reeves Roger H, Roizen Nancy, Santoro Stephanie, Sherman Stephanie L., Talib Nasreen, Tapia Ignacio E., Walsh Kyle M., Warren Steven F., White A. Nicole, Wong G. William, Yi, John S

Translational Science of Rare Diseases, 15 April 2021

2021

Kognition bei Down-Syndrom: Entwicklung über die Lebensspanne und neuropsychologische Diagnostik im Erwachsenenalter :

Cognition in Down’s Syndrome: Development across the Life Span and Neuropsychological Assessment in Adults

Loosli, S.V., Schmidt, L., Nübling, G., Wlasich, E., Prix, C., Danek, A., Levin, J.

Fortschritte der Neurologie – Psychiatrie, January 2021

2020

The AT(N) framework for Alzheimer’s disease in adults with Down syndrome

S. Rafii, B. M. Ances, N. Schupf, S. J. Krinsky-McHale, M. Mapstone, W. Silverman, I. Lott, W. Klunk, E. Head, B. Christian, F. Lai, H. D. Rosas, S. Zaman, M. E. Petersen, A. Strydom, J. Fortea, B. Handen, S. O’Bryant

Alzheimer’s Dementia, Diagnosis, Assessment & Disease monitoring, July 2020

2020

Further understanding the connection between Alzheimer’s disease and Down syndrome

M. Snyder, L. J. Bain, A. M. Brickman, M. C. Carrillo, A. J. Esbensen, J. M. Espinosa, F. Fernandez, J. Fortea, S. L. Hartley, E. Head, J. Hendrix, P. S. Kishnani, F. Lai, P. Lao, C. Lemere, W. Mobley, E. J. Mufson, H. Potter, S. H. Zaman, A-C Granholm, H. D. Rosas, A. Strydom, M. Sie Whitten, M. S. Rafii

Alzheimer’s Dementia, March 2020

2019

Eine deutsche Fassung der CAMDEX-DS (Cambridge Examination for Mental Disorders of Older People with Down’s Syndrome and Others with Intellectual Disabilities).

Ein Diagnoseverfahren zur Erfassung von Demenz bei Menschen mit einem Down-Syndrom

Nübling, G., Loosli, S. V., Wlasich, E., Prix, C., Schönecker, S., Freudelsperger, L., Smrzka, N., Strydom, A. M., Zaman, S. H., Benejam, B., Missios, J., Meister, R., Danek, A., Levin, J

Zeitschrift für Geriatrie und Gerontologie, 53, 546-551 August 2019

2018

Alzheimer’s disease in Down syndrome: An overlooked population for prevention trials.

A. Strydom, A. Coppus, R. Blesa, A. Danek, J. Fortea, J. Hardy, J. Levin, G. Nuebling, AS Rebillat, C. Ritchie, C. van Duijn, S. Zaman, H. Zetterberg

Alzheimers Dement (N Y). 13 Dec 2018